Eric Kofman

storyteller

Eric Kofman could never decide what he wanted to be when he grew up — and he still can't.

By day he builds tools to pull meaning out of the genome.

By night he writes original musicals and songs, draws cartoons, and paints.

Scroll down to see the results of both his day job and his moonlighting.

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Now booking

Snow White & the Seven Million Followers

In a not-so-distant future, AI has decimated the creator economy and left the world’s influencers fighting for their survival. A mysterious new social media platform offers them one last chance to maintain their fame, relevance, and livelihoods. But is the deal too good to be true?

A darkly funny new musical about social media and AI, the collapse of authenticity, and the unsettling possibility that the most dangerous lies are the ones we most desperately want to believe.

AMT Theater · October 15–18

Get tickets @seven.million.musical

Original rock opera

An original rock opera about Fritz Haber — the chemist whose work fed billions yet also fueled the worst excesses of the Great War. Though the events it depicts took place a century ago, Haber’s examination of its protagonist’s life and work raises still-relevant questions about the role scientists should play as moral stewards of scientific progress.

Staged as a concert-style reading at the Armory in Boston, 2019, to an audience of over a hundred. A few reviews from attendees:

“We were singing the lyrics after the show was over!”

“The lyrics are outstanding — intelligent, alliterative, and they do a wonderful job carrying the story.”

Currently seeking producers interested in helping develop Haber toward a full theatrical production. Reach out and let’s chat →

Watch the concert-style reading on YouTube Read the synopsis Hear demo recordings

The Haber staged reading in performance — cast in lab coats at music stands before a full house

Close-up of performers at the Haber staged reading

Sketch comedy

Laugh Tracks

An original musical-comedy sketch show at ImprovBoston (2018), co-written with Hannah Petosa and performed with Hannah Petosa, and Ethan Wilcox. The Laugh Tracks team, as they called themselves, took first place in ImprovBoston’s Battle Royale — billed as a “sketch and standup battle to the comedy death.”

Artwork and cartoons published in the New Yorker

A Daily Cartoon, plus illustrations for Daily Shouts pieces by Ginny Hogan.

Daily Cartoon: Groundhog Day Daily Cartoon → Punishments for Children That I’d Love as an Adult Daily Shouts → Valentine’s Day Cards for Libertarians Daily Shouts →

Cartoons

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Paintings

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the full sketchbook on instagram → @eric.kofman

Publications and tools

Fig. 1 — Publication

Peer-reviewed research in Nature

“Single-cell and isoform-specific translational profiling of the mouse brain”, Nature 2026 — co-first author. Read the full article for the methods, figures, and findings.

Read the paper

Fig. 2 — Publication

STAMP in Nature Methods

“Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes” — contributed the computational analyses. Nature Methods, 2021.

Read the paper

Fig. 3 — Publication

RNA base editors in Nature Communications

“Expanded palette of RNA base editors for comprehensive RBP–RNA interactome studies” — second author. Nature Communications, 2024.

Read the paper

Fig. 4 — Publication

FLARE in BMC Bioinformatics

“FLARE: a fast and flexible workflow for identifying RNA editing foci” — a Snakemake pipeline for finding regions enriched for RNA editing. Kofman, Yee, Medina-Munoz & Yeo, 2023.

Read the paper

Fig. 5 — Review

Immune checkpoint genomics in Genome Medicine

“Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine” — co-first author. A review in Genome Medicine, 2018.

Read the review

Fig. 6 — Software

MARINE

MARINE is an open-source algorithm designed for RNA edit-calling at single-cell and isoform-level resolution, developed for the single-cell STAMP publication and maintained on GitHub. Built for reproducibility — clone it, run it, cite it.

View on GitHub

Fig. 7 — Software

FLARE

The FLARE open-source pipeline itself, maintained on GitHub under the Yeo Lab and free for anyone to clone, run, and build on.

View on GitHub

Scientific writing and illustration

Research stories written and illustrated for Epigenie.

Fig. 8 — Writing & illustration

Burn After Reading: YTHDF2 and cancer’s protein problems

How the m6A mRNA reader YTHDF2 helps cancer cells manage their protein problems.

Read the article

Fig. 9 — Writing & illustration

How to Change Your Mini-Mind

5hmC’s role in neurodevelopment and Alzheimer’s disease.

Read the article

Fig. 10 — Writing & illustration

Where’s the Cancer Driver?

MethSig cuts through the background noise to identify oncogenic promoter hypermethylation.

Read the article

Fig. 11 — Writing & illustration

Selfies from Beyond the Grave

CELFIE deconvolutes cell-free DNA methylation messages.

Read the article